All Cancer starts with inflammation
Tumor-promoting inflammation is one of the hallmarks of cancer. It has been shown that cancer development is strongly influenced by both chronic and acute inflammation process. Progress in research on inflammation revealed a connection between inflammatory processes and neoplastic transformation, the progression of tumour, and the development of metastases and recurrences. Moreover, the tumour invasive procedures (both surgery and biopsy) affect the remaining tumour cells by increasing their survival, proliferation and migration. One of the concepts explaining this phenomenon is an induction of a wound healing response. While in normal tissue it is necessary for tissue repair, in tumor tissue, induction of adaptive and innate immune response related to wound healing, stimulates tumor cell survival, angiogenesis and extravasation of circulating tumor cells. It has become evident that certain types of immune response and immune cells can promote tumor progression more than others.
Source :
https://www.sciencedirect.com/science/article/pii/S1507136720300602
